Clinical Connections

Evidence in action

 

The most interesting articles encountered during our literature surveillance.

Evidence in action

ASCO Annual Meeting

The American Society of Clinical Oncology (ASCO) held its annual meeting June 3-7, 2022, in Chicago, Illinois, with the theme “Advancing Equitable Cancer Care Through Innovation.” Several thousand studies were presented at the first in-person meeting since 2019....

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Genomic sequencing of solid tumors to guide cancer therapy

Genetic testing is a rapidly growing area in which technology can outpace the understanding of its appropriate use. In the area of tumor genetics, this is especially true. An increasing number of cancer therapies are being developed and approved, many of which target...

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The impact of low-value cardiovascular care

In a scientific statement released for publication, the American Heart Association Council on Quality of Care and Outcomes Research examines the issue of low-value cardiovascular care, including a discussion of the scope and impact of this problem and a review of the...

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Same day discharge following joint replacement surgery

A recent study published in the Journal of Bone & Joint Surgery examined same-day discharge following total joint replacement in patients considered to be at increased risk for adverse events. ((Reddy NC, Prentice HA, Paxton EW, et al. Association Between Same-Day...

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New guidance for evaluation of chest pain

The American Heart Association and American College of Cardiology recently released a comprehensive guideline for evaluation and diagnosis of chest pain.((Gulati M, Levy PD, Mukherjee D, et al. 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and...

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Management of stable coronary artery disease

Coronary artery disease (CAD) is a common condition which exists across a spectrum ranging from asymptomatic, subclinical disease to acute, life-threatening events. Between these extremes is a large population of patients with stable disease. The role of...

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Colorectal cancer screening

On May 18th, 2021, the U.S. Preventive Services Task Force (USPSTF) issued a revised recommendation statement on screening for colorectal cancer. ((US Preventive Services Task Force. Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation...

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Trends in cancer incidence and mortality

A cross sectional study published in the JAMA Open Network in April 2021 examines U.S. population-based cancer statistics and census data to predict trends in cancer incidence and mortality over the next 20 years.((Estimated Projection of US Cancer Incidence and Death...

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PET radiotracers in prostate cancer

The FDA recently approved two new radiotracers for use in prostate cancer. Gallium (Ga)-68 prostate-specific membrane antigen (PSMA) was the first, approved in December of 2020. PSMA is a protein unique to prostate tissue which is found in high concentration in...

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